Zepbound

Anyone else getting emotional over your weight loss? I'm interested in other folks' experiences on the emotional changes associated with significant weight loss. In terms of context, I (62m) have basically been overweight my entire adult life. I was a chubby kid and received all the taunts that the bullies felt like dishing out. In high school I got a little buff due to playing football/baseball and I was on the wrestling team. After college, I pretty much led a sedentary life as a software developer. My highest weight was about 320, but I've typically weighed between 285-300 for most of the past 10 yrs or so. Most folks wouldn't have guessed that I weighed as much as I did because I carried it pretty well. I'm sort of built like an O lineman in football... big shoulders/arms, big legs, etc. There were periods of going to the gym to get healthier, and I could lose 20-30 lbs but I kept getting sick of being hungry all the time and would gain it all back. In Dec 2024, my doc recommended zepbound but I declined as I just didn't want to add another medication and wasn't sure about side effects, etc. In the spring of 2025, I talked with a couple members of my extended family and they set me at ease because of their own experiences on zepbound. Then later in June 2025, I met with my doc again and said I'm ready to start the shots. In June 2025 I started on the initial 2.5 mg dose, and subsequently lost 45 lbs between then and my next doctor's visit in Dec 2025. The doc was amazed that I had lost that much weight on the initial dose. It turns out that I had plateaued a bit in the 2-3 weeks before the doctor visit, so my doc agreed to bump me up to the 5mg dose where I'm at now. Since then, I've lost another twenty lbs for a total loss of 65 so far, with another 35 to go to reach my goal of 200. I think the last time I weighed 200 lbs was as a freshman in high school - LOL. I feel like my results so far are about as amazing as anyone could hope for. I've had basically no side-effects other than I sometimes get a little nauseous when I might normally feel hungry. But a protein shake or Clif Bar takes care of that in minutes. I can now go for long walks without back pain (my back has been a mess over the last 20 years and in 2023, I had a spinal cord stimulator installed to eliminate sciatica and other related back pain). My wife and I will be joining a gym and I actually can't wait to get back into some regular - but not overly intense - weight training. Geez, I haven't lifted in probably 20 yrs but looking forward to getting back into it. As you can imagine, I've had to essentially buy a whole new wardrobe and that's when I really started getting emotional. I sort of lean into western wear (I live in Central Texas) and recently bought new jeans and belts and a few shirts. I can now fit into size 36 jeans which I can't even remember the last time I could do that. I'm not bragging but I look GOOD in this new stuff (my wife has been telling me this non-stop recently so I decided to believe her :) ). After basically hating the way I look most of my adult life, it's sometimes overwhelming to look in the mirror and see how good I look comparatively speaking. I've got pecs and I've got the beginnings of a six pack (yes, even 62 yr olds can have abs that pop apparently). I have a little bit of loose skin here and there, and I still have a little more weight to lose, but I now have every confidence in the world that I can reach my goal. I'm not ashamed to admit that on a few occasions, my emotions have sort of short-circuited and I just break down and cry like a baby. These are mostly tears of joy, but also there's this slight feeling that I don't deserve this after living my life as an overweight person. I'm mainly curious if others have been dealing with similar emotions as you start to achieve significant weight loss. If you made it all the way to the end, thanks for listening and sorry for the long post...

Time for new clothes I started my Zepbound journey the begging of July at 306 pounds wearing a 2X on top and 3X/4X on bottom. I'm now down to 219 pounds at 5'9" and wearing a L top and XL bottoms. I really don't know what size jeans or pants I wear now. I still have another 30-40 pounds to lose. Should I get myself a pair of jeans as a reward now? Should I just keep wearing my leggings until I get my goal of 180/190 pounds? Sun dresses seem to fit for a good while also and I live in South Texas so it's warm. What is everyone else doing?

Whelp… it finally happened The timing of this was especially shady, as our insurance benefit selections closed on the 16th (2 days before they supposedly sent the letters). During elections, I specifically looked up Zepbound on the formulary and noted it was still listed as PA required, exactly as it’s always been. And now this. Unfortunately my husbands benefits closed literally yesterday, so there’s literally nothing I can do. I’m just well and truly screwed. You would think these kind of changes would allow you to find new insurance, but the game is rigged against us.

GLP-1 Friendly Dr in San Antonio Any San Antonians here who have GP doctors that are advocates of weight loss meds? I have a prescribing doctor via telehealth that I’m very happy with. However, I need a new GP. I went to UT Health S.A. because I figured those doctors would be super up to date on the meds. Well, very first thing the doc asked me was why I am still on Zepbound when I have a healthy BMI. She brought up five times that I should be off it. So she’s not going to work! ETA: to be clear, I’m looking for a general practitioner for annual checkups or when I get sick. I don’t need a GLP-1 prescriber - just one who supports me using them. Thanks!

GLP-1 Friendly Dr in San Antonio Any San Antonians here who have GP doctors that are advocates of weight loss meds? I have a prescribing doctor via telehealth that I’m very happy with. However, I need a new GP. I went to UT Health S.A. because I figured those doctors would be super up to date on the meds. Well, very first thing the doc asked me was why I am still on Zepbound when I have a healthy BMI. She brought up five times that I should be off it. So she’s not going to work! ETA: to be clear, I’m looking for a general practitioner for annual checkups or when I get sick. I don’t need a GLP-1 prescriber - just one who supports me using them. Thanks!

Food Recommendations for Upset Stomach Hey guys. I’ve royally pissed off my stomach. Ate at texas roadhouse two nights ago and had my usual steak and salad. I ate more than normal and ended up getting sulfur burps midday the next day, and then that evening had rough stomach pains and vomited with really no relief. Pepto and gas x carried me through the rest of the night and to midday yesterday. I felt better! Young, lively, ready to take on the world! Then, my slow self thought that since my stomach felt better, I’ll eat Indian food and eat my normal little bit. Fast forward to early hours this morning. My stomach hurt SO bad. Like terrible. No nausea initially just upper left quad pain. Then I vomited profusely and the pain immediately subsided. Needless to say… I owe my stomach and myself an apology. I got the message loud and clear. So far this morning I’m nursing a hot green tea with a touch of honey. And a keifer yogurt drink. I plan on eating rice and chicken for dinners for the next few days. But what do you recommend for the in betweens? Normally it’s eggs and cheese sticks. But the thought of those also makes me nauseous. Learn from me… Zepbound shows no mercy if you play games. I’ve been on it for almost a year and idk why I decided to go buck wild and act like I had no sense. 🙄 Edit: timing is off. Texas was three nights ago. But what came up the first time was definitely Texas roadhouse 😖

How good of a case do I have for my insurance to approve gastric bypass? I have Cigna through my employer for insurance. I had them a couple of years ago and at the time, my employer plan did not cover any weight loss medications or procedures whatsoever. I have struggled with my weight my whole life and have tried just about everything you can think of. I have had success off and on but ultimately I end up gaining everything plus more back. I have been trying so hard the last 2 years to finally get my life under control and make the lifestyle changes to make it stick. I am 5'2'' and at my heaviest I was 371 lbs. I lost 40lbs on my own and was maintaining it but unable to make much more progress until my insurance FINALLY approved zepbound because of my sleep apnea. I have been on zepbound since September 2025 and have lost another 40 lbs. My insurance sent me a letter last month stating they will no longer cover zepbound or any GLP1 meds for weight loss, even if you have sleep apnea. I was devastated. I did not want to regain the weight and wasn't sure what to do. Even with the shots, I knew it would be hard to get to my goal weight (150). I started looking into gastric bypass and found out they supposedly cover it. I got my insurance to email me their policy and it looks like I qualify. You just have to have a BMI over 35 and have been on a supervised weight loss program for 6 months. I have been working with my doctor for over 2 years for weight loss, been on zepbound since September, and since January (when my Cigna insurance took effect), I had to use an app called Omada where you weigh in on their scale every week and follow lessons and talk to a health coach. I started with a bariatric program that is a 3 month program. I am currently going through all the appointments with them, logging my food on the baritastic app, etc. They will submit everything to my insurance at my last preop appt at the end of next month. At that point they will see if the insurance approves it and then schedule my surgery. I am so nervous and worried that my insurance is going to screw me over and say I don't need it. Does anyone here have experience with Cigna and getting rejected and were you able to get it approved eventually? I just feel like I'm going to be so stressed until it gets approved because I don't know what other options I have at this point. I'm so tired of fighting with my weight and dealing with insurance companies that won't help you with anything other than crap pills like phentermine that don't help me or health coaching.

Maintenance Dosing I have been on zepbound weekly shots for almost a year now. I am finally where I want to be with my weight and would like to maintain. I am back to 2.5 dose and it is going well, although sometimes I still lose a bit. It is not a bad thing, I just don’t want to get too low as I am already on the edge. When I don’t take it I end up binging a lot. I was wondering if anyone has ever taken it once or twice a month instead of 4 times and if that is possible? Or, I know my dose is already the lowest dose but is it possible to maybe not draw out the full 5 mL? Just some thoughts in my head. Any input is extremely welcome ☺️ thanks!

Weight Gain? Hi everyone, I’m on my second week of 2.5mgs of Zepbound and I’m frustrated. I weighed in heavier this week than I was last week and I could truly feel the food aversion happen an hour after taking it and well into the 3 days of my first week. I’ve noticed I’m hungry and suffering with a stomach ache today, but thinking about food makes me feel sick. Would love to hear your thoughts and feedback on your experience.

Zepbound to Wegovy - unusual question I’m sort of an outlier. I’ve been a subpar responder to zepbound. Didn’t lose until 10mg and have stalled on 15mg for almost a year. I’ve been on zepbound 2.5years and still have at least 45lbs to lose. I’m considering switching to Wegovy, as I’m wondering if my body needs more GLP hormone (zepbound is mostly GIP w a lower concentration of glp), AND since the higher dose came to market. Anyone have an experience similar to me where they didn’t lose much on Tirzepatide and switched to Wegovy? Most posts I’ve found are people being forced to switch for insurance reasons (or in previous years, shortage reasons).

Scared to start & Don’t know where to start Hi Everyone! My insurance recently cut my coverage for Zepbound unfortunately. I have 3 weeks left and was looking at getting compounded options soon. I Don’t know the risks and Don’t know where to start. Can anyone provide some good reliable information? It would be greatly appreciated!!

GLP1 and Zepbound prescription I’m super frustrated and just felt like I needed a place to vent. I was diagnosed with moderate to severe OSA six months ago and have begun using a CPAP. My ENT also suggested that I utilize a GLP one medication to treat my sleep apnea so I called my insurance and they informed me that they would cover Zepbound provided. I had moderate to severe OSA. They said they wouldn’t prescribe it. I needed my PCP to. I made an appointment and got a prescription for Zepbound for my PCP. I submitted a prior authorization of my insurance and wouldn’t you know what they denied it I called my insurance and they said it’s because I don’t have an AHI of 15 or more which they previously never mentioned I have an AHI of 11. I let them know that my sleep doctor still provided his diagnosis of moderate to severe OSA and they said I would need to appeal the decision and obtain a letter from my sleep doctor stating that he believes I still have moderate to severe OSA despite my AHI. I called my sleep doctor to get the letter and he hits me with that. He doesn’t believe in GLP one medication‘s to treat sleep apnea, even though FDA approved them because they technically “don’t treat sleep apnea and only treat weight” and “have been shown to cause cancer” which I’ve never heard before my PCP disagrees with. I asked for a study or some source where he’s getting the cancer association from and he said he would send one but so far haven’t received anything. I’m wondering why he’s so against it when FDA approved it and if anyone’s run into anything similar because honestly, it’s super defeating and frustrating to know that an approved medication is being withheld for me that could potentially help me get off a CPAP someday.